Exploring the Potential of Green Coffee Extract for Wound HealingTreatment

humaryanto, humaryanto and Rahman, Ave (2019) Exploring the Potential of Green Coffee Extract for Wound HealingTreatment. annual conference on environmental science, society and its aplication.

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Official URL: https://iopscience.iop.org/article/10.1088/1755-13...


Roasted coffee powder is used as wound dressing in Indonesian traditional medicine. Coffee bean have several properties, such as chlorogenic acid, that can facilitate the wound healing. Green coffee has a higher chlorogenic acid. This study is to exploring the effect of green coffee beans extract for wound healing in rats. Extraction of green Robusta coffee used ethanol 70% with ratio 1:3 and dried by rotary evaporation. There were 6 male rats in each group. The incission wound were held in back with diameter size 1,5 centimeter under lidocaine anesthetic. Treatment group were given extract every day d for 15 days. Control group were not given treatment. Animal were sacrificed at day 16th for histophalology assessment of fibroblast and collagen using hematoxylin eosin stain. Percentage of complete wound closuring on day 16 in treatment group was 83%, whereas control group were only 66%. There were not significant different in fibroblast and collagen scoring between two groups (p> 0,05). Green coffee extract can accelerate wound healing.

Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Kedokteran dan Ilmu Kesehatan > Ilmu Keperawatan
Depositing User: Humaryanto
Date Deposited: 25 Jun 2020 09:33
Last Modified: 25 Jun 2020 09:33
URI: https://repository.unja.ac.id/id/eprint/12243

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