Yusriyyah, Desy (2025) Uji Aktivitas Antijamur Hair Tonic Ekstrak Jamur Grigit (Schizophyllum commune) terhadap Pertumbuhan Malassezia furfur sebagai Materi Pengayaan Praktikum Mikologi dalam Bentuk E-Booklet. S1 thesis, UNIVERSITAS JAMBI.
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Abstract
Iklim tropis dengan suhu dan kelembaban yang tinggi mendukung pertumbuhan jamur Malassezia furfur, yaitu spesies jamur lipofilik yang hidup pada folikel rambut dan keratin kulit, penyebab ketombe. Kondisi ini juga dipicu oleh sekresi minyak kulit berlebih yang mempercepat perkembangbiakan M. furfur. Pemakaian obat antijamur dan produk perawatan dapat mencegah terbentuknya ketombe, namun penggunaan antijamur berbahan kimia secara terus-menerus dapat menimbulkan efek samping yang tidak dinginkan. Jamur grigit (Schizophyllum commune) mengandung senyawa bioaktif yang berpotensi menghambat pertumbuhan jamur. Pemanfaatan ekstrak jamur grigit dalam hair tonic dapat memberikan solusi alami yang lebih aman untuk mengatasi ketombe. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur dan konsentrasi terbaik hair tonic ekstrak jamur grigit (S. commune) terhadap pertumbuhan M. furfur. Penelitian ini dilaksanakan di Laboratorium Pendidikan Biologi dan Laboratorium Fakultas Peternakan Universitas Jambi. Metode yang digunakan pada penelitian ini, yaitu metode eksperimen dengan desain Rancangan Acak Lengkap (RAL) yang terdiri dari 6 perlakuan, yaitu kontrol positif (P0), kontrol negatif (P1), dan konsentrasi 10% (P2), 30% (P3), 50% (P4), dan 70% (P5). Parameter yang diamati berupa diameter zona hambat, uji organoleptik, uji viskositas, uji pH, dan uji iritasi. Data yang diperoleh dari pengamatan zona hambat dan pengukuran pH dianalisis menggunakan Analysis of Variance (ANOVA), sedangkan data uji viskositas dianalisis menggunakan uji Kruskal-wallis pada taraf kepercayaan 95%. Sementara itu, data uji organoleptik dan uji iritasi kulit dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa hair tonic ekstrak jamur grigit (S. commune) memiliki aktivitas antijamur terhadap pertumbuhan M. furfur. Berdasarkan analisis statistik ANOVA [F(2,20) = 22,64,P = < 0,001]. Hasil uji DNMRT menunjukkan bahwa diameter zona hambat terbesar adalah perlakuan konsentrasi 70% (P5), yaitu 33,96 mm yang berbeda signifikan dengan perlakuan lainnya. Berdasarkan uji evaluasi sediaan masing-masing perlakuan memiliki variasi karakteristik organoleptik, nilai pH yang sesuai dengan kulit kepala dan tidak menyebabkan iritasi, serta viskositas yang aman untuk diaplikasikan pada kulit. Kesimpulan dalam penelitian ini, yaitu terdapat aktivitas antijamur hair tonic ekstrak jamur grigit terhadap pertumbuhan jamur M. furfur, dengan konsentrasi terbaik yaitu 50%. Kata Kunci : Jamur grigit, Hair tonic, Malasezzia furfur. Tropical climate with high temperature and humidity supports the growth of Malassezia furfur fungus, a lipophilic fungal species that lives in hair follicles and skin keratin, causing dandruff. This condition is also triggered by excess skin oil secretion that accelerates the development of M. furfur. The use of antifungal drugs and skincare products can prevent dandruff from forming, but continuous use of chemical antifungals can cause unwanted side effects. The grigit fungus (Schizophyllum commune) contains bioactive compounds that have the potential to inhibit the growth of fungi. The use of grigit mushroom extract in hair tonic can provide a safer natural solution to overcome dandruff. This study aims to determine the antifungal activity and the best concentration of grigit mushroom extract (S.commune) hair tonic on the growth of M. furfur. This study was conducted in the Biology Education Laboratory and the Faculty of Animal Husbandry Laboratory, Jambi University. The method used in this study, namely the experimental method with a Completely Randomized Design (CRD) design consisting of 6 treatments, namely positive control (P0), negative control (P1), and concentrations of 10% (P2), 30% (P3), 50% (P4), and 70% (P5). The parameters observed were the diameter of the inhibition zone, organoleptic test, viscosity test, pH test, and irritation test. Data obtained from the observation of the inhibition zone and pH measurements were analyzed using Analysis of Variance (ANOVA), while viscosity test data were analyzed using the Kruskal-Wallis test at a 95% confidence level. Meanwhile, organoleptic test data and skin irritation tests were analyzed descriptively. The results showed that hair tonic extract of grigit mushrooms (S.commune) had antifungal activity against the growth of M. furfur. Based on the statistical analysis of ANOVA [F(2,20) = 22.64,P = <0.001]. The results of the DNMRT test showed that the largest inhibition zone diameter was the 70% concentration treatment (P5), which was 33.96 mm which was significantly different from other treatments. Based on the evaluation test of the preparation, each treatment had variations in organoleptic characteristics, pH values that were in accordance with the scalp and did not cause irritation, and viscosity that was safe for application to the skin. The conclusion in this study is that there is antifungal activity of hair tonic extract of grigit mushrooms against the growth of M. furfur fungi, with the best concentration of 50%. Keywords: Grigit mushrooms, Hair tonic, Malasezzia furfur.
| Type: | Thesis (S1) |
|---|---|
| Uncontrolled Keywords: | Keywords: Grigit mushrooms, Hair tonic, Malasezzia furfur. |
| Subjects: | L Education > L Education (General) |
| Divisions: | Fakultas Keguruan dan Ilmu Pendidikan > Pendidikan Biologi |
| Depositing User: | DESY YUSRIYYAH |
| Date Deposited: | 08 Jul 2025 02:11 |
| Last Modified: | 08 Jul 2025 02:11 |
| URI: | https://repository.unja.ac.id/id/eprint/81772 |
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